A weekly briefing on clinical and healthcare AI that examines new studies, product launches and vendor claims, with attention to evidence quality and conflicts of interest. It draws out implications for health-system leaders, such as governance, evaluation and security exposure.

Underlying Conditions covers medicine, public health and health policy, with issues that pair current news events with sourced explanation of the science and the policy behind them. Recent issues examined lung cancer screening in the context of the Pope's diagnosis and the investigation of reported lab-acquired plague cases in Irkutsk and Chicago.

Eric Topol, a cardiologist and researcher, unpacks new biomedical papers, especially on aging, immunology and AI in medicine, and interviews prominent figures. Readers get plain-language explanations of the underlying data and what it means for health.

Christina Pagel, a UCL operational research professor, examines how evidence and data bear on politics, health and science, with a current focus on the second Trump administration's health policy and related political actions. Each issue combines sourced, data-driven analysis with a hand-coded tracker and a clear critical viewpoint.