Long-form essays by neuroscientist Erik Hoel on AI's effects on culture, human freedom and the future, written with literary and philosophical flourishes. Readers get a strongly argued, personal point of view on technology, science and society.

Long-form essays on biology, drug discovery and machine learning, currently a three-part series on whether organoids have delivered on their promise. The author, who works on health data philanthropy, offers skeptical, opinionated analysis of the scientific literature with occasional life and job updates.

Research-informed essays and podcast episodes on ADHD, hypercuriosity and evolutionary neuroscience, written by a King's College London neuroscientist who has ADHD herself. Readers get a critical look at the medical model of ADHD, medication, competing theories and non-drug approaches.

Each issue takes an everyday emotional or behavioral scenario and explains the brain mechanisms behind it, citing specific studies and brain regions. It ends with a practical question or technique the reader can apply, such as in the moment before a reflexive decision.